Modeling DNA-translocation through nanopores: Two case studies
نویسندگان
چکیده
In the second part we focus on the translocation of elongated cylindrical particles (oligomers, nanorods, etc.) through a solid state nanopore. Particular emphasis is put on the interplay of electrophoresis, electroosmosis, and osmotic pressure beyond the realm of small Debye lengths. We find that the net potential energy difference across the membrane may be of opposite sign for short and long particles. Thermal noise thus leads to biased diffusion through the pore in opposite directions. The specific particle length at which this transport inversion occurs can be controlled by means of a membrane gate electrode [3].
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